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Sensibilización periférica: es un descenso del umbral de dolor y un incremento en la respuesta de los receptores del dolor.Mild-based mostly control of Gi/o signaling downstream of opioid receptors has also been realized with selective caged agonists that may be unveiled by UV light. Caged agonists from the opioid receptors Leu5-enkephalin (LE) a